Has anyone compared the middle wheel click pressure to the mx master 3 which I find requires way too much pressure for constant use?

For you, I've just compared them. The M650 L requires fractionally *more* pressure to click the middle button than the MX Master 3. It doesn't sound like it will suit your purpose. Suggest to head to a bricks and mortar retailer and try some out.

Can the mouse wheel be configured to scroll vertically and horizontally in spreadsheets?

it can scroll horizontally but only in specific apps. see logitech website

Is a usb connector included? some reviews & answers seem to be giving differing information on this front.

Yes, it's inside the mouse, there is a panel on the bottom of the mouse you slide back to reveal the battery compartment and the location where the wireless usb adapter is stored. It isn't clear if those reviewers didn't know this or it genuinely was missing from their unit

Brand	Logitech
Product Dimensions	11.82 x 6.56 x 4.15 cm; 160 Grams
Batteries	1 AA batteries required. (included)
Item model number	910-006238
Manufacturer	Logitech
Series	Signature M650 L Full Size Wireless Mouse
Colour	Offwhite
Wattage	3600 watts
Power Source	Battery Powered
Hardware Platform	PC, Mac, Chromebook
Operating System	Windows® 10, 11 or later, Linux, Android™ 8.0 or later, iPadOS 13.4 or later, Chrome OS, macOS® 10.10 or later
Average Battery Life (in hours)	24 months
Are Batteries Included	Yes
Lithium Battery Packaging	Batteries contained in equipment
Item Weight	160 g
Guaranteed software updates until	unknown

Signature M650 L Full Size Wireless Mouse - For Large Sized Hands, 2-Year Battery, Silent Clicks, Customisable Side Buttons, Bluetooth, for PC/Mac/Multi-Device/Chromebook - White

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