Hi, If I use this on the spots where she goes and she goes to a new place to retaliate, would you recommend this to treat the whole house?

When you say treat the whole house do you mean as a preventative? If so I don't know how that would work, but if you are asking about treating other areas in the house she may urinate on then yes I would say that would work just fine.

Can I use this in my Rug Doctor?

You could but it would be unessary and pretty expensive. I would spot with the Simple Solution and then use the rug dr.

are the continuous bottles refillable

This version of our Simple Solution Urine Destroyer is not refillable. We hope that you may find this information helpful. For more information visit us at www,HeroPetBrands.com or call us at 800-272-6336. We are here to help! Sincerely, Hero Pet Brands

Is this a concentrate to be mixed with water?

There are no directions on the container stating that this should be mixed with water so I use it full strength. One time, I was running out so I put about 1/8 cup of water (1:1 ratio for amount left) into the dispenser bottle. It still worked on the odors I used it on. I would not recommend doing that though unless it's your last resort until you can get more. The product description states it contains water as one of the main ingredients so it is already diluted. One can presume it is to the proper strength.

ASIN	B00WJQMO3E
Best Sellers Rank	200,920 in Pet Supplies ( See Top 100 in Pet Supplies ) 222 in Dog Stain Removers
Brand	Simple Solution
Brand Name	Simple Solution
Contains Liquid Contents?	Yes
Contains liquid contents	Yes
Country of Origin	United Kingdom
Customer Reviews	4.2 out of 5 stars 488 Reviews
Global Trade Identification Number	00010279113622
Item Type Name	Simple Solution Pet Urine Destroyer, 32 ounce Pour, Made in USA
Item Volume	5 Litres
Item Weight	0.84 Pounds
Item volume	5 Litres
Item weight	0.84 Pounds
Manufacturer	OUT! International
Surface Recommendation	Carpet
Surface recommendation	Carpet
UPC	010279113622
Unit Count	1892.7 millilitre
Unit count	1892.7 millilitre

Simple Solution Urine Destroyer Enzymatic Cleaner | Pet Stain and Odor Remover with 2X Pro-bacteria Cleaning Power | 32 Ounces

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