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Meratrim is a proprietary plant extract blend for weight management derived from two plants, sphaeranthus indicus and garcinia mangostana, traditionally used in southeast asian culture. Meratrim has been shown in two independent, randomized, double-blind, placebo-controlled clinical studies to significantly reduce body weight, bmi, and waist circumference within 8 weeks when used in combination with a diet and exercise plan. Meratrim appears to achieve this by modulating the accumulation of fat while simultaneously increasing fat burning. Toxicological studies on meratrim have demonstrated a wide margin of safety. In vitro studies demonstrate that meratrim modulates the expression of biomarkers that control adipogenesis and lipogenesis as follows:Reduces the expression of the peroxisome proliferator-activated receptor gamma (PPAR) hormone receptor. PPAR induces adipocyte-specific genes involved in the formation and growth of fat cells.Reduces the expression of adipocyte differentiation-related protein (ADRP). This is a signaling protein which facilitates the uptake of fatty acidsPerilipins are adipocyte proteins that inhibit fat breakdown by restricting access of lipase to the lipid droplet.Capsicum capsimax capsicum extract is a proprietary encapsulated form of premium, highly concentrated natural capsicum fruit extract made from hot red peppers. Capsaicinoids are a group of compounds which cause the “heat” found in hot peppers. In fact, over the past 30 years, studies including animal and human subjects support the potential of red hot capsicum and capsaicinoids as a safe, effective ingredient to aid in weight management. Benefits of capsicum and capsaicinoids have shown that it helps manage appetite, supports lipolysis, and helps diet-induced thermogenesis.
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منذ أسبوعين
منذ 5 أيام